- During the gap between Seasons 2 and 3, because of the low rate of global threat, Ant-Man went solo again, the plans for expanding the Avengers were cancelled and the original Avengers temporarily broke up.
- Also, when Black Widow realizes that the other Avengers followed her to AIM'S hideout, the Hulk is shown to have transformed back into Bruce Banner, as a result of the Avengers being modeled after their MCU counterparts.
Appearing in "Adapting to Change"
- Captain America (Steve Rogers)
- Iron Man (Tony Stark)
- Black Widow (Natasha Romanoff)
- Falcon (Sam Wilson)
- Hulk (Bruce Banner)
- Hawkeye (Clint Barton)
- Friday (First appearance)
- Masters of Evil (First appearance)
- Beetle (Abner Jenkins)
- Screaming Mimi (Melissa Gold) (First appearance)
- Goliath (Erik Josten) (First appearance)
- Scientist Supreme (First appearance)
- Thanos (Mentioned)
- Red Skull (Johann Schmidt) (Mentioned)
- Ant-Man (Scott Lang) (Mentioned)